Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice

Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice

Diet-induced muscle insulin resistance is associated with expansion of extracellular matrix (ECM) components, such as collagens, and the expression of collagen-binding integrin, α2β1. Integrins transduce signals from ECM via their cytoplasmic domains, which bind to intracellular integrin-binding pro...

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Bibliographic Details
Main Authors: Kang, Li, Mokshagundam, Shilpa, Reuter, Bradley, Lark, Daniel S., Sneddon, Claire C., Hennayake, Chandani, Williams, Ashley S., Bracy, Deanna P., James, Freyja D., Pozzi, Ambra, Zent, Roy, Wasserman, David H.
Format: Online
Language:English
Published: American Diabetes Association 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878430/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878430/

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