Increased Survival and Function of Mesenchymal Stem Cell Spheroids Entrapped in Instructive Alginate Hydrogels

Mesenchymal stem cell (MSC)-based therapies are under investigation for tissue repair but suffer from poor cell persistence and engraftment upon transplantation. When entrapped in an adhesive biomaterial, MSC spheroids exhibited improved survival and proangiogenic growth factor secretion in vitro an...

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Bibliographic Details
Main Authors: Ho, Steve S., Murphy, Kaitlin C., Binder, Bernard Y.K., Vissers, Caroline B., Leach, J. Kent
Format: Online
Language:English
Published: AlphaMed Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878334/