Activity-Regulated Cytoskeleton-Associated Protein Controls AMPAR Endocytosis through a Direct Interaction with Clathrin-Adaptor Protein 2123

Activity-Regulated Cytoskeleton-Associated Protein Controls AMPAR Endocytosis through a Direct Interaction with Clathrin-Adaptor Protein 2123

The activity-regulated cytoskeleton-associated (Arc) protein controls synaptic strength by facilitating AMPA receptor (AMPAR) endocytosis. Here we demonstrate that Arc targets AMPAR to be internalized through a direct interaction with the clathrin-adaptor protein 2 (AP-2). We show that Arc overexpre...

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Bibliographic Details
Main Authors: DaSilva, Luis L. P., Wall, Mark J., P. de Almeida, Luciana, Wauters, Sandrine C., Januário, Yunan C., Müller, Jürgen, Corrêa, Sonia A. L.
Format: Online
Language:English
Published: Society for Neuroscience 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877669/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877669/

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