Mice lacking Programmed cell death-1 show a role for CD8+ T cells in long-term immunity against blood-stage malaria

Even after years of experiencing malaria, caused by infection with Plasmodium species, individuals still have incomplete immunity and develop low-density parasitemia on re-infection. Previous studies using the P. chabaudi (Pch) mouse model to understand the reason for chronic malaria, found that mic...

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Bibliographic Details
Main Authors: Horne-Debets, Joshua M., Karunarathne, Deshapriya S., Faleiro, Rebecca J., Poh, Chek Meng, Renia, Laurent, Wykes, Michelle N.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877649/