Neurodevelopmental Problems in Non-Syndromic Craniosynostosis

Craniosynostosis is the premature fusion of calvarial sutures, resulting in deformed craniofacial appearance. Hence, for a long time, it has been considered an aesthetic disorder. Fused sutures restrict growth adjacent to the suture, but compensatory skull growth occurs to accommodate the growing br...

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Main Authors: Shim, Kyu-Won, Park, Eun-Kyung, Kim, Ju-Seong, Kim, Yong-Oock, Kim, Dong-Seok
Format: Online
Language:English
Published: The Korean Neurosurgical Society 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877546/
id pubmed-4877546
recordtype oai_dc
spelling pubmed-48775462016-05-25 Neurodevelopmental Problems in Non-Syndromic Craniosynostosis Shim, Kyu-Won Park, Eun-Kyung Kim, Ju-Seong Kim, Yong-Oock Kim, Dong-Seok Pediatric Issue Craniosynostosis is the premature fusion of calvarial sutures, resulting in deformed craniofacial appearance. Hence, for a long time, it has been considered an aesthetic disorder. Fused sutures restrict growth adjacent to the suture, but compensatory skull growth occurs to accommodate the growing brain. The primary goal for the management of this craniofacial deformity has been to release the constricted skull and reform the distorted shape of the skull vault. However, the intellectual and behavioral prognosis of affected children has also been taken into consideration since the beginning of the modern era of surgical management of craniosynostosis. A growing body of literature indicates that extensive surgery, such as the whole-vault cranioplasty approach, would result in better outcomes. In addition, the age at treatment is becoming a major concern for optimal outcome in terms of cosmetic results as well as neurodevelopment. This review will discuss major concerns regarding neurodevelopmental issues and related factors. The Korean Neurosurgical Society 2016-05 2016-05-10 /pmc/articles/PMC4877546/ /pubmed/27226855 http://dx.doi.org/10.3340/jkns.2016.59.3.242 Text en Copyright © 2016 The Korean Neurosurgical Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Shim, Kyu-Won
Park, Eun-Kyung
Kim, Ju-Seong
Kim, Yong-Oock
Kim, Dong-Seok
spellingShingle Shim, Kyu-Won
Park, Eun-Kyung
Kim, Ju-Seong
Kim, Yong-Oock
Kim, Dong-Seok
Neurodevelopmental Problems in Non-Syndromic Craniosynostosis
author_facet Shim, Kyu-Won
Park, Eun-Kyung
Kim, Ju-Seong
Kim, Yong-Oock
Kim, Dong-Seok
author_sort Shim, Kyu-Won
title Neurodevelopmental Problems in Non-Syndromic Craniosynostosis
title_short Neurodevelopmental Problems in Non-Syndromic Craniosynostosis
title_full Neurodevelopmental Problems in Non-Syndromic Craniosynostosis
title_fullStr Neurodevelopmental Problems in Non-Syndromic Craniosynostosis
title_full_unstemmed Neurodevelopmental Problems in Non-Syndromic Craniosynostosis
title_sort neurodevelopmental problems in non-syndromic craniosynostosis
description Craniosynostosis is the premature fusion of calvarial sutures, resulting in deformed craniofacial appearance. Hence, for a long time, it has been considered an aesthetic disorder. Fused sutures restrict growth adjacent to the suture, but compensatory skull growth occurs to accommodate the growing brain. The primary goal for the management of this craniofacial deformity has been to release the constricted skull and reform the distorted shape of the skull vault. However, the intellectual and behavioral prognosis of affected children has also been taken into consideration since the beginning of the modern era of surgical management of craniosynostosis. A growing body of literature indicates that extensive surgery, such as the whole-vault cranioplasty approach, would result in better outcomes. In addition, the age at treatment is becoming a major concern for optimal outcome in terms of cosmetic results as well as neurodevelopment. This review will discuss major concerns regarding neurodevelopmental issues and related factors.
publisher The Korean Neurosurgical Society
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877546/
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