Can agrin cerebrospinal fluid concentration be used as an early biomarker for Alzheimer's disease?

The need for effective treatments halting Alzheimer's disease (AD) urges the discovery of the earliest possible biomarkers. Agrin is increased in the early stages of AD and is involved in amyloid-β (Aβ) fibrillation and synaptogenesis. We investigated the potential of agrin as an early AD cereb...

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Bibliographic Details
Main Authors: Del Campo Milan, Marta, Zuroff, Leah, Jimenez, Connie R., Scheltens, Philip, Teunissen, Charlotte E.
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876904/