TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis

To evaluate the role of TCF7L2, a key regulator of glucose homeostasis, in estradiol (E2) and progesterone (P4)-modulated glucose metabolism, mouse insulinoma cells (MIN6) and human liver cancer cells (hepG2 and HUH7) were treated with physiological concentrations of E2 or P4 in the up- and down-reg...

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Bibliographic Details
Main Authors: Dong, Fengqin, Ling, Qi, Ye, Dan, Zhang, Zhe, Shu, Jing, Chen, Guoping, Fei, Yang, Li, Chengjiang
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876840/