Tumor necrosis factor reduces Plasmodium falciparum growth and activates calcium signaling in human malaria parasites
•TNF is able to decrease parasitemia in P. falciparum‐infected RBCs.•TNF induced rises in intracellular calcium concentration, which were blocked by the purinergic receptor agonists KN62 and A438079.•Interfering with intra‐ or extracellular calcium release by thapsigargin or EGTA also block TNF‐indu...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier Pub. Co
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876768/ |