The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity

The microRNA-29 (miR-29) family is among the most abundantly expressed microRNA in the pancreas and liver. Here, we investigated the function of miR-29 in glucose regulation using miR-29a/b-1 (miR-29a)-deficient mice and newly generated miR-29b-2/c (miR-29c)-deficient mice. We observed multiple inde...

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Bibliographic Details
Main Authors: Dooley, James, Garcia-Perez, Josselyn E., Sreenivasan, Jayasree, Schlenner, Susan M., Vangoitsenhoven, Roman, Papadopoulou, Aikaterini S., Tian, Lei, Schonefeldt, Susann, Serneels, Lutgarde, Deroose, Christophe, Staats, Kim A., Van der Schueren, Bart, De Strooper, Bart, McGuinness, Owen P., Mathieu, Chantal, Liston, Adrian
Format: Online
Language:English
Published: American Diabetes Association 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876765/