Epigenetic Upregulation of Metallothionein 2A by Diallyl Trisulfide Enhances Chemosensitivity of Human Gastric Cancer Cells to Docetaxel Through Attenuating NF-κB Activation

Epigenetic Upregulation of Metallothionein 2A by Diallyl Trisulfide Enhances Chemosensitivity of Human Gastric Cancer Cells to Docetaxel Through Attenuating NF-κB Activation

Aims: Metallothionein 2A (MT2A) and nuclear factor-kappaB (NF-κB) are both involved in carcinogenesis and cancer chemosensitivity. We previously showed decreased expression of MT2A and IκB-α in human gastric cancer (GC) associated with poor prognosis of GC patients. The present study investigated th...

Full description

Bibliographic Details
Main Authors: Pan, Yuanming, Lin, Shuye, Xing, Rui, Zhu, Min, Lin, Bonan, Cui, Jiantao, Li, Wenmei, Gao, Jing, Shen, Lin, Zhao, Yuanyuan, Guo, Mingzhou, Wang, Ji Ming, Huang, Jiaqiang, Lu, Youyong
Format: Online
Language:English
Published: Mary Ann Liebert, Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876530/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876530/

Similar Items