LRRK2 Regulates Voltage-Gated Calcium Channel Function

Voltage-gated Ca2+ (CaV) channels enable Ca2+ influx in response to membrane depolarization. CaV2.1 channels are localized to the presynaptic membrane of many types of neurons where they are involved in triggering neurotransmitter release. Several signaling proteins have been identified as important...

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Bibliographic Details
Main Authors: Bedford, Cade, Sears, Catherine, Perez-Carrion, Maria, Piccoli, Giovanni, Condliffe, Steven B.
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876133/