LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells

Adenosine monophosphate-activated protein kinase (AMPK) acts as a fuel gauge that maintains energy homeostasis in both normal and cancerous cells, and has emerged as a tumor suppressor. The present study aims to delineate the functional relationship between AMPK and transforming growth factor beta (...

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Bibliographic Details
Main Authors: Li, Nian-Shuang, Zou, Jun-Rong, Lin, Hui, Ke, Rong, He, Xiao-Ling, Xiao, Lu, Huang, Deqiang, Luo, Lingyu, Lv, Nonghua, Luo, Zhijun
Format: Online
Language:English
Published: Springer Netherlands 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875963/