Collagens VI and XII form complexes mediating osteoblast interactions during osteogenesis

Bone formation is precisely regulated by cell-cell communication in osteoblasts. We have previously demonstrated that genetic deletion of Col6a1 or Col12a1 impairs osteoblast connections and/or communication in mice, resulting in bone mass reduction and bone fragility. Mutations of the genes encodin...

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Bibliographic Details
Main Authors: Izu, Yayoi, Ezura, Yoichi, Koch, Manuel, Birk, David E., Noda, Masaki
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875952/