Integrated genomic analyses identify frequent gene fusion events and VHL inactivation in gastrointestinal stromal tumors

Integrated genomic analyses identify frequent gene fusion events and VHL inactivation in gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. We sequenced nine exomes and transcriptomes, and two genomes of GISTs for integrated analyses. We detected 306 somatic variants in nine GISTs and recurrent protein-altering mutations in 29 g...

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Bibliographic Details
Main Authors: Kang, Guhyun, Yun, Hongseok, Sun, Choong-Hyun, Park, Inho, Lee, Seungmook, Kwon, Jekeun, Do, Ingu, Hong, Min Eui, Van Vrancken, Michael, Lee, Jeeyun, Park, Joon Oh, Cho, Jeonghee, Kim, Kyoung-Mee, Sohn, Tae Sung
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872731/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872731/

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