Novel strategies to target the ubiquitin proteasome system in multiple myeloma

Multiple myeloma (MM) is a hematological malignancy characterized by the accumulation of plasma cells in the bone marrow (BM). The success of the proteasome inhibitor bortezomib in the treatment of MM highlights the importance of the ubiquitin proteasome system (UPS) in this particular cancer. Despi...

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Bibliographic Details
Main Authors: Lub, Susanne, Maes, Ken, Menu, Eline, De Bruyne, Elke, Vanderkerken, Karin, Van Valckenborgh, Els
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872730/