Reduced Uterine Perfusion Pressure (RUPP) Model of Preeclampsia in Mice

Preeclampsia (PE) is a pregnancy-induced hypertension with proteinuria that typically develops after 20 weeks of gestation. A reduction in uterine blood flow causes placental ischemia and placental release of anti-angiogenic factors such as sFlt-1 followed by PE. Although the reduced uterine perfusi...

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Bibliographic Details
Main Authors: Fushima, Tomofumi, Sekimoto, Akiyo, Minato, Takahiro, Ito, Takuya, Oe, Yuji, Kisu, Kiyomi, Sato, Emiko, Funamoto, Kenichi, Hayase, Toshiyuki, Kimura, Yoshitaka, Ito, Sadayoshi, Sato, Hiroshi, Takahashi, Nobuyuki
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871336/