Multiple Transduction Pathways Mediate Thyrotropin Receptor Signaling in Preosteoblast-Like Cells

It has been shown that the TSH receptor (TSHR) couples to a number of different signaling pathways, although the Gs-cAMP pathway has been considered primary. Here, we measured the effects of TSH on bone marker mRNA and protein expression in preosteoblast-like U2OS cells stably expressing TSHRs. We d...

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Bibliographic Details
Main Authors: Boutin, Alisa, Neumann, Susanne, Gershengorn, Marvin C.
Format: Online
Language:English
Published: Endocrine Society 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870888/