Estradiol in the Preoptic Area Regulates the Dopaminergic Response to Cocaine in the Nucleus Accumbens

The sex-steroid hormone estradiol (E2) enhances the psychoactive effects of cocaine, as evidenced by clinical and preclinical studies. The medial preoptic area (mPOA), a region in the hypothalamus, is a primary neural locus for neuroendocrine integration, containing one of the richest concentrations...

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Bibliographic Details
Main Authors: Tobiansky, Daniel J, Will, Ryan G, Lominac, Kevin D, Turner, Jonathan M, Hattori, Tomoko, Krishnan, Krittika, Martz, Julia R, Nutsch, Victoria L, Dominguez, Juan M
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869059/