Screening of cytoprotectors against methotrexate-induced cytogenotoxicity from bioactive phytochemicals
As a well known anti-neoplastic drug, the cytogenotoxicity of methotrexate (MTX) has received more attention in recent years. To develop a new cytoprotector to reduce the risk of second cancers caused by methotrexate, an umu test combined with a micronucleus assay was employed to estimate the cytopr...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
PeerJ Inc.
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867711/ |