Pre-existence and Persistence of Resistant Minority Hepatitis C Virus Variants in Genotype 1-Infected Patients Treated With Simeprevir/Peginterferon/Ribavirin

Pre-existence and Persistence of Resistant Minority Hepatitis C Virus Variants in Genotype 1-Infected Patients Treated With Simeprevir/Peginterferon/Ribavirin

Deep sequencing analyses in HCV genotype 1-infected patients treated with simeprevir/peginterferon/ribavirin showed that pre-existing minority HCV variants did not impact treatment outcome and emerging resistant variants in patients failing treatment were not persisting at minority levels

Bibliographic Details
Main Authors: Fevery, Bart, Thys, Kim, Van Eygen, Veerle, Verbinnen, Thierry, Van Rossem, Elizabeth, Buelens, Annemie, Aerssens, Jeroen, Witek, James, Picchio, Gaston, De Meyer, Sandra, Lenz, Oliver
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866569/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866569/

Similar Items