Functional Analyses of Transcription Factor Binding Sites that Differ between Present-Day and Archaic Humans

We analyze 25 previously identified transcription factor binding sites that carry DNA sequence changes that are present in all or nearly all present-day humans, yet occur in the ancestral state in Neandertals and Denisovans, the closest evolutionary relatives of humans. When the ancestral and derive...

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Bibliographic Details
Main Authors: Weyer, Sven, Pääbo, Svante
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866544/