Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

Although memory T cells within barrier tissues can persist as permanent residents, at least some exchange with blood. The extent to which this occurs is unclear. Here we show that memory CD4+ T cells in mouse skin are in equilibrium with the circulation at steady state. These cells are dispersed thr...

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Bibliographic Details
Main Authors: Collins, Nicholas, Jiang, Xiaodong, Zaid, Ali, Macleod, Bethany L., Li, Jane, Park, Chang Ook, Haque, Ashraful, Bedoui, Sammy, Heath, William R., Mueller, Scott N., Kupper, Thomas S., Gebhardt, Thomas, Carbone, Francis R.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866325/