The small GTPases Ras and Rap1 bind to and control TORC2 activity

The small GTPases Ras and Rap1 bind to and control TORC2 activity

Target of Rapamycin Complex 2 (TORC2) has conserved roles in regulating cytoskeleton dynamics and cell migration and has been linked to cancer metastasis. However, little is known about the mechanisms regulating TORC2 activity and function in any system. In Dictyostelium, TORC2 functions at the fron...

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Bibliographic Details
Main Authors: Khanna, Ankita, Lotfi, Pouya, Chavan, Anita J., Montaño, Nieves M., Bolourani, Parvin, Weeks, Gerald, Shen, Zhouxin, Briggs, Steven P., Pots, Henderikus, Van Haastert, Peter J. M., Kortholt, Arjan, Charest, Pascale G.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865869/

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