Slug-upregulated miR-221 promotes breast cancer progression through suppressing E-cadherin expression

Slug-upregulated miR-221 promotes breast cancer progression through suppressing E-cadherin expression

It is generally regarded that E-cadherin is downregulated during tumorigenesis via Snail/Slug-mediated E-cadherin transcriptional reduction. However, this transcriptional suppressive mechanism cannot explain the failure of producing E-cadherin protein in metastatic breast cancer cells after overexpr...

Full description

Bibliographic Details
Main Authors: Pan, Yi, Li, Jing, Zhang, Yaqin, Wang, Nan, Liang, Hongwei, Liu, Yuan, Zhang, Chen-Yu, Zen, Ke, Gu, Hongwei
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865839/

Similar Items

Similar Items