Development and Preclinical Application of an Immunocompetent Transplant Model of Basal Breast Cancer with Lung, Liver and Brain Metastases

Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer that is associated with a poor prognosis and for which no targeted therapies currently exist. In order to improve preclinical testing for TNBC that relies primarily on using human xenografts in immunodeficient mice, we ha...

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Bibliographic Details
Main Authors: Aprelikova, Olga, Tomlinson, Christine C., Hoenerhoff, Mark, Hixon, Julie A., Durum, Scott K., Qiu, Ting-hu, He, Siping, Burkett, Sandra, Liu, Zi-Yao, Swanson, Steven M., Green, Jeffrey E.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865188/