Impaired immunological synapse in sperm associated antigen 6 (SPAG6) deficient mice

Sperm associated antigen 6 (SPAG6), a component of the central apparatus of the “9 + 2” axoneme, plays a central role in ciliary and flagellar motility; but, its contribution to adaptive immunity and immune system development is completely unknown. While immune cells lack a cilium, the immunological...

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Bibliographic Details
Main Authors: Cooley, Lauren Folgosa, El Shikh, Mohey Eldin, Li, Wei, Keim, Rebecca C., Zhang, Zhengang, Strauss, Jerome F., Zhang, Zhibing, Conrad, Daniel H.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864328/