Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States

Whether codon usage fine-tunes mRNA translation in mammals remains controversial, with recent papers suggesting that production of proteins in specific Gene Ontological (GO) pathways can be regulated by actively modifying the codon and anticodon pools in different cellular conditions. In this work,...

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Bibliographic Details
Main Authors: Rudolph, Konrad L. M., Schmitt, Bianca M., Villar, Diego, White, Robert J., Marioni, John C., Kutter, Claudia, Odom, Duncan T.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864286/