Uropathogenic Escherichia coli Metabolite-Dependent Quiescence and Persistence May Explain Antibiotic Tolerance during Urinary Tract Infection

Recurrent urinary tract infections (UTIs) affect 10 to 40% of women. In up to 77% of those cases, the recurrent infections are caused by the same uropathogenic E. coli (UPEC) strain that caused the initial infection. Upon infection of urothelial transitional cells in the bladder, UPEC appear to ente...

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Bibliographic Details
Main Authors: Leatham-Jensen, Mary P., Mokszycki, Matthew E., Rowley, David C., Deering, Robert, Camberg, Jodi L., Sokurenko, Evgeni V., Tchesnokova, Veronika L., Frimodt-Møller, Jakob, Krogfelt, Karen A., Leth Nielsen, Karen, Frimodt-Møller, Niels, Sun, Gongqin, Cohen, Paul S.
Format: Online
Language:English
Published: American Society for Microbiology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863606/