The pharmacology and therapeutic potential of (−)-huperzine A

(−)-Huperzine A (1) is an alkaloid isolated from a Chinese club moss. Due to its potent neuroprotective activities, it has been investigated as a candidate for the treatment of neurodegenerative diseases, including Alzheimer’s disease. In this review, we will discuss the pharmacology and therapeutic...

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Main Authors: Tun, Maung Kyaw Moe, Herzon, Seth B
Format: Online
Language:English
Published: Dove Medical Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863551/
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spelling pubmed-48635512016-05-16 The pharmacology and therapeutic potential of (−)-huperzine A Tun, Maung Kyaw Moe Herzon, Seth B Review (−)-Huperzine A (1) is an alkaloid isolated from a Chinese club moss. Due to its potent neuroprotective activities, it has been investigated as a candidate for the treatment of neurodegenerative diseases, including Alzheimer’s disease. In this review, we will discuss the pharmacology and therapeutic potential of (−)-huperzine A (1). Synthetic studies of (−)-huperzine A (1) aimed at enabling its development as a pharmaceutical will be described. Dove Medical Press 2012-09-05 /pmc/articles/PMC4863551/ /pubmed/27186124 http://dx.doi.org/10.2147/JEP.S27084 Text en © 2012 Tun and Herzon, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Tun, Maung Kyaw Moe
Herzon, Seth B
spellingShingle Tun, Maung Kyaw Moe
Herzon, Seth B
The pharmacology and therapeutic potential of (−)-huperzine A
author_facet Tun, Maung Kyaw Moe
Herzon, Seth B
author_sort Tun, Maung Kyaw Moe
title The pharmacology and therapeutic potential of (−)-huperzine A
title_short The pharmacology and therapeutic potential of (−)-huperzine A
title_full The pharmacology and therapeutic potential of (−)-huperzine A
title_fullStr The pharmacology and therapeutic potential of (−)-huperzine A
title_full_unstemmed The pharmacology and therapeutic potential of (−)-huperzine A
title_sort pharmacology and therapeutic potential of (−)-huperzine a
description (−)-Huperzine A (1) is an alkaloid isolated from a Chinese club moss. Due to its potent neuroprotective activities, it has been investigated as a candidate for the treatment of neurodegenerative diseases, including Alzheimer’s disease. In this review, we will discuss the pharmacology and therapeutic potential of (−)-huperzine A (1). Synthetic studies of (−)-huperzine A (1) aimed at enabling its development as a pharmaceutical will be described.
publisher Dove Medical Press
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863551/
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