Neuroglobin in Breast Cancer Cells: Effect of Hypoxia and Oxidative Stress on Protein Level, Localization, and Anti-Apoptotic Function

Neuroglobin in Breast Cancer Cells: Effect of Hypoxia and Oxidative Stress on Protein Level, Localization, and Anti-Apoptotic Function

The over-expression of human neuroglobin (NGB), a heme-protein preferentially expressed in the brain, displays anti-apoptotic effects against hypoxic/ischemic and oxidative stresses enhancing neuron survival. As hypoxic and oxidative stress injury frequently occurs in fast proliferating neoplastic t...

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Bibliographic Details
Main Authors: Fiocchetti, Marco, Cipolletti, Manuela, Leone, Stefano, Naldini, Antonella, Carraro, Fabio, Giordano, Daniela, Verde, Cinzia, Ascenzi, Paolo, Marino, Maria
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858147/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858147/

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