Type 2 Diabetes, Diabetes Genetic Score and Risk of Decreased Renal Function and Albuminuria: A Mendelian Randomization Study

Type 2 Diabetes, Diabetes Genetic Score and Risk of Decreased Renal Function and Albuminuria: A Mendelian Randomization Study

•A MR study was conducted to explore the causal association between T2D and decreased renal function.•Weighted T2D genetic risk score (GRS) was used as the instrumental variable (IV).•A higher T2D_GRS was associated with higher risk of decreased glomerular filtration rate (GFR).•T2D estimated by the...

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Bibliographic Details
Main Authors: Xu, Min, Bi, Yufang, Huang, Ya, Xie, Lan, Hao, Mingli, Zhao, Zhiyun, Xu, Yu, Lu, Jieli, Chen, Yuhong, Sun, Yimin, Qi, Lu, Wang, Weiqing, Ning, Guang
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856750/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856750/

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