Eosinophil differentiation in the bone marrow is promoted by protein tyrosine phosphatase SHP2

SHP2 participates in multiple signaling events by mediating T-cell development and function, and regulates cytokine-dependent granulopoiesis. To explore whether and how SHP2 can regulate bone-marrow eosinophil differentiation, we investigate the contribution of SHP2 in the bone-marrow eosinophil dev...

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Bibliographic Details
Main Authors: Xia, L-x, Hua, W, Jin, Y, Tian, B-p, Qiu, Z-w, Zhang, C, Che, L-q, Zhou, H-b, Wu, Y-f, Huang, H-q, Lan, F, Ke, Y-h, Lee, J J, Li, W, Ying, S-m, Chen, Z-h, Shen, H-h
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855658/