Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer

Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer

D’Amico et al. show that Dkk1 exerts immune-suppressive effects by directly targeting β-catenin in murine and human MDSCs and promoting their activation in cancer.

Bibliographic Details
Main Authors: D’Amico, Lucia, Mahajan, Sahil, Capietto, Aude-Hélène, Yang, Zhengfeng, Zamani, Ali, Ricci, Biancamaria, Bumpass, David B., Meyer, Melissa, Su, Xinming, Wang-Gillam, Andrea, Weilbaecher, Katherine, Stewart, Sheila A., DeNardo, David G., Faccio, Roberta
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854727/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854727/

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