The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma

The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma

The REL gene, encoding the NF-κB subunit c-Rel, is frequently amplified in B-cell lymphoma and functions as a tumour-promoting transcription factor. Here we report the surprising result that c-rel–/– mice display significantly earlier lymphomagenesis in the c-Myc driven, Eμ-Myc model of B-cell lymph...

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Bibliographic Details
Main Authors: Hunter, J E, Butterworth, J A, Zhao, B, Sellier, H, Campbell, K J, Thomas, H D, Bacon, C M, Cockell, S J, Gewurz, B E, Perkins, N D
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853301/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853301/

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