Structure and evolutionary history of a large family of NLR proteins in the zebrafish

Multicellular eukaryotes have evolved a range of mechanisms for immune recognition. A widespread family involved in innate immunity are the NACHT-domain and leucine-rich-repeat-containing (NLR) proteins. Mammals have small numbers of NLR proteins, whereas in some species, mostly those without adapti...

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Bibliographic Details
Main Authors: Howe, Kerstin, Schiffer, Philipp H., Zielinski, Julia, Wiehe, Thomas, Laird, Gavin K., Marioni, John C., Soylemez, Onuralp, Kondrashov, Fyodor, Leptin, Maria
Format: Online
Language:English
Published: The Royal Society 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852459/