PharmGKB Drug Data Normalization with NDF-RT

PharmGKB Drug Data Normalization with NDF-RT

The Pharmacogenomics Knowledge Base (PharmGKB) [1] is a publicly available central resource for pharmacogenomics data and knowledge, which is being widely employed into clinical practice and thus requires using clinical terminologies. Hence, harmonizing PharmGKB drug data with well annotated drug te...

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Main Authors: Zhu, Qian, Freimuth, Robert R, Pathak, Jyotishman, Chute, Christopher G
Format: Online
Language:English
Published: American Medical Informatics Association 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852296/
id pubmed-4852296
recordtype oai_dc
spelling pubmed-48522962016-05-02 PharmGKB Drug Data Normalization with NDF-RT Zhu, Qian Freimuth, Robert R Pathak, Jyotishman Chute, Christopher G Articles The Pharmacogenomics Knowledge Base (PharmGKB) [1] is a publicly available central resource for pharmacogenomics data and knowledge, which is being widely employed into clinical practice and thus requires using clinical terminologies. Hence, harmonizing PharmGKB drug data with well annotated drug terminologies will facilitate its integration with other related resources and support data representation, interpretation, and exchange within and across heterogeneous sources and applications. In this study, we extracted drug and drug class from PharmGKB, and mapped them to National Drug File Reference Terminology (NDF-RT) [2], which is integrated into RxNorm specified by U.S. Meaningful Use regulations. And the evaluated mapping results will be provided to PharmGKB for further investigation and collaboration. American Medical Informatics Association 2013-03-18 /pmc/articles/PMC4852296/ /pubmed/24303334 Text en ©2013 AMIA - All rights reserved.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Zhu, Qian
Freimuth, Robert R
Pathak, Jyotishman
Chute, Christopher G
spellingShingle Zhu, Qian
Freimuth, Robert R
Pathak, Jyotishman
Chute, Christopher G
PharmGKB Drug Data Normalization with NDF-RT
author_facet Zhu, Qian
Freimuth, Robert R
Pathak, Jyotishman
Chute, Christopher G
author_sort Zhu, Qian
title PharmGKB Drug Data Normalization with NDF-RT
title_short PharmGKB Drug Data Normalization with NDF-RT
title_full PharmGKB Drug Data Normalization with NDF-RT
title_fullStr PharmGKB Drug Data Normalization with NDF-RT
title_full_unstemmed PharmGKB Drug Data Normalization with NDF-RT
title_sort pharmgkb drug data normalization with ndf-rt
description The Pharmacogenomics Knowledge Base (PharmGKB) [1] is a publicly available central resource for pharmacogenomics data and knowledge, which is being widely employed into clinical practice and thus requires using clinical terminologies. Hence, harmonizing PharmGKB drug data with well annotated drug terminologies will facilitate its integration with other related resources and support data representation, interpretation, and exchange within and across heterogeneous sources and applications. In this study, we extracted drug and drug class from PharmGKB, and mapped them to National Drug File Reference Terminology (NDF-RT) [2], which is integrated into RxNorm specified by U.S. Meaningful Use regulations. And the evaluated mapping results will be provided to PharmGKB for further investigation and collaboration.
publisher American Medical Informatics Association
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852296/
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