Transformed Recombinant Enrichment Profiling Rapidly Identifies HMW1 as an Intracellular Invasion Locus in Haemophilus influenzae

Many bacterial species actively take up and recombine homologous DNA into their genomes, called natural competence, a trait that offers a means to identify the genetic basis of naturally occurring phenotypic variation. Here, we describe “transformed recombinant enrichment profiling” (TREP), in which...

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Bibliographic Details
Main Authors: Mell, Joshua Chang, Viadas, Cristina, Moleres, Javier, Sinha, Sunita, Fernández-Calvet, Ariadna, Porsch, Eric A., St. Geme, Joseph W., Nislow, Corey, Redfield, Rosemary J., Garmendia, Junkal
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849778/