Identification of a Potent and Broad-Spectrum Hepatitis C Virus Fusion Inhibitory Peptide from the E2 Stem Domain

Identification of a Potent and Broad-Spectrum Hepatitis C Virus Fusion Inhibitory Peptide from the E2 Stem Domain

Hepatitis C virus (HCV) envelope proteins E1 and E2 play an essential role in virus entry. However, the fusion mechanisms of HCV remain largely unclear, hampering the development of efficient fusion inhibitors. Here, we developed two cell-based membrane fusion models that allow for screening a pepti...

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Bibliographic Details
Main Authors: Chi, Xiaojing, Niu, Yuqiang, Cheng, Min, Liu, Xiuying, Feng, Yetong, Zheng, Fuxiang, Fan, Jingjing, Li, Xiang, Jin, Qi, Zhong, Jin, Li, Yi-Ping, Yang, Wei
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848495/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848495/

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