Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways
The present study confirmed that Srx-1 overexpression could protect cardiomyocyte from SI/R-induced injury by suppressing PI3K/AKT-regulated mitochondria dependent apoptosis. Therefore, the present study will support a promising therapeutic avenue for the treatment of ischaemic cardiovascular diseas...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Portland Press Ltd.
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847177/ |