Antibacterial Applications of Nanodiamonds

Antibacterial Applications of Nanodiamonds

Bacterial infectious diseases, sharing clinical characteristics such as chronic inflammation and tissue damage, pose a major threat to human health. The steady increase of multidrug-resistant bacteria infections adds up to the current problems modern healthcare is facing. The treatment of bacterial...

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Main Authors: Szunerits, Sabine, Barras, Alexandre, Boukherroub, Rabah
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847075/
id pubmed-4847075
recordtype oai_dc
spelling pubmed-48470752016-05-04 Antibacterial Applications of Nanodiamonds Szunerits, Sabine Barras, Alexandre Boukherroub, Rabah Review Bacterial infectious diseases, sharing clinical characteristics such as chronic inflammation and tissue damage, pose a major threat to human health. The steady increase of multidrug-resistant bacteria infections adds up to the current problems modern healthcare is facing. The treatment of bacterial infections with multi-resistant germs is very difficult, as the development of new antimicrobial drugs is hardly catching up with the development of antibiotic resistant pathogens. These and other considerations have generated an increased interest in the development of viable alternatives to antibiotics. A promising strategy is the use of nanomaterials with antibacterial character and of nanostructures displaying anti-adhesive activity against biofilms. Glycan-modified nanodiamonds (NDs) revealed themselves to be of great promise as useful nanostructures for combating microbial infections. This review summarizes the current efforts in the synthesis of glycan-modified ND particles and evaluation of their antibacterial and anti-biofilm activities. MDPI 2016-04-12 2016-04 /pmc/articles/PMC4847075/ /pubmed/27077871 http://dx.doi.org/10.3390/ijerph13040413 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Szunerits, Sabine
Barras, Alexandre
Boukherroub, Rabah
spellingShingle Szunerits, Sabine
Barras, Alexandre
Boukherroub, Rabah
Antibacterial Applications of Nanodiamonds
author_facet Szunerits, Sabine
Barras, Alexandre
Boukherroub, Rabah
author_sort Szunerits, Sabine
title Antibacterial Applications of Nanodiamonds
title_short Antibacterial Applications of Nanodiamonds
title_full Antibacterial Applications of Nanodiamonds
title_fullStr Antibacterial Applications of Nanodiamonds
title_full_unstemmed Antibacterial Applications of Nanodiamonds
title_sort antibacterial applications of nanodiamonds
description Bacterial infectious diseases, sharing clinical characteristics such as chronic inflammation and tissue damage, pose a major threat to human health. The steady increase of multidrug-resistant bacteria infections adds up to the current problems modern healthcare is facing. The treatment of bacterial infections with multi-resistant germs is very difficult, as the development of new antimicrobial drugs is hardly catching up with the development of antibiotic resistant pathogens. These and other considerations have generated an increased interest in the development of viable alternatives to antibiotics. A promising strategy is the use of nanomaterials with antibacterial character and of nanostructures displaying anti-adhesive activity against biofilms. Glycan-modified nanodiamonds (NDs) revealed themselves to be of great promise as useful nanostructures for combating microbial infections. This review summarizes the current efforts in the synthesis of glycan-modified ND particles and evaluation of their antibacterial and anti-biofilm activities.
publisher MDPI
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847075/
_version_ 1613571675657338880

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