Dual Regulation of R-Type CaV2.3 Channels by M1 Muscarinic Receptors
Voltage-gated Ca2+ (CaV) channels are dynamically modulated by G protein-coupled receptors (GPCR). The M1 muscarinic receptor stimulation is known to enhance CaV2.3 channel gating through the activation of protein kinase C (PKC). Here, we found that M1 receptors also inhibit CaV2.3 currents when the...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Korean Society for Molecular and Cellular Biology
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844939/ |