Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood

Childhood obesity is a major public health issue. Here we investigated whether differential DNA methylation was associated with childhood obesity. We studied DNA methylation profiles in whole blood from 78 obese children (mean BMI Z-score: 2.6) and 71 age- and sex-matched controls (mean BMI Z-score:...

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Bibliographic Details
Main Authors: Huang, R C, Garratt, E S, Pan, H, Wu, Y, Davis, E A, Barton, S J, Burdge, G C, Godfrey, K M, Holbrook, J D, Lillycrop, K A
Format: Online
Language:English
Published: Taylor & Francis 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844195/