RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

The DNA replication machinery invariably encounters obstacles that slow replication fork progression, and threaten to prevent complete replication and faithful segregation of sister chromatids. The resulting replication stress activates ATR, the major kinase involved in resolving impaired DNA replic...

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Bibliographic Details
Main Authors: Kanu, Nnennaya, Zhang, Tianyi, Burrell, Rebecca A., Chakraborty, Atanu, Cronshaw, Janet, Da Costa, Clive, Grönroos, Eva, Pemberton, Helen N., Anderton, Emma, Gonzalez, Laure, Sabbioneda, Simone, Ulrich, Helle D., Swanton, Charles, Behrens, Axel
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842010/