The Role of Genome Accessibility in Transcription Factor Binding in Bacteria
ChIP-seq enables genome-scale identification of regulatory regions that govern gene expression. However, the biological insights generated from ChIP-seq analysis have been limited to predictions of binding sites and cooperative interactions. Furthermore, ChIP-seq data often poorly correlate with in...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841574/ |