The Role of Genome Accessibility in Transcription Factor Binding in Bacteria

ChIP-seq enables genome-scale identification of regulatory regions that govern gene expression. However, the biological insights generated from ChIP-seq analysis have been limited to predictions of binding sites and cooperative interactions. Furthermore, ChIP-seq data often poorly correlate with in...

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Bibliographic Details
Main Authors: Gomes, Antonio L. C., Wang, Harris H.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841574/