TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy

TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy

Primary central nervous system lymphoma (PCNSL) is an aggressive variant of diffuse large B-cell lymphoma (DLBCL) confined to the CNS. TP53 mutations (MUT-TP53) were investigated in the context of MIR34A/B/C- and DAPK promoter methylation status, and associated with clinical outcomes in PCNSL patien...

Full description

Bibliographic Details
Main Authors: Munch-Petersen, Helga D., Asmar, Fazila, Dimopoulos, Konstantinos, Areškevičiūtė, Aušrinė, Brown, Peter, Girkov, Mia Seremet, Pedersen, Anja, Sjö, Lene D., Heegaard, Steffen, Broholm, Helle, Kristensen, Lasse S., Ralfkiaer, Elisabeth, Grønbæk, Kirsten
Format: Online
Language:English
Published: BioMed Central 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840983/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840983/

Similar Items