Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division
Dystrophin is expressed in differentiated myofibers where it is required for sarcolemmal integrity, and loss-of-function mutations in its gene result in Duchenne Muscular Dystrophy (DMD), a disease characterized by progressive and severe skeletal muscle degeneration. Here we found that dystrophin is...
Main Authors: | , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839960/ |