The Diversity and Molecular Evolution of B-Cell Receptors during Infection

B-cell receptors (BCRs) are membrane-bound immunoglobulins that recognize and bind foreign proteins (antigens). BCRs are formed through random somatic changes of germline DNA, creating a vast repertoire of unique sequences that enable individuals to recognize a diverse range of antigens. After encou...

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Bibliographic Details
Main Authors: Hoehn, Kenneth B., Fowler, Anna, Lunter, Gerton, Pybus, Oliver G.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839220/