Environmental Correlation Analysis for Genes Associated with Protection against Malaria
Genome-wide searches for loci involved in human resistance to malaria are currently being conducted on a large scale in Africa using case-control studies. Here, we explore the utility of an alternative approach—“environmental correlation analysis, ECA,” which tests for clines in allele frequencies a...
Main Authors: | Mackinnon, Margaret J., Ndila, Carolyne, Uyoga, Sophie, Macharia, Alex, Snow, Robert W., Band, Gavin, Rautanen, Anna, Rockett, Kirk A., Kwiatkowski, Dominic P., Williams, Thomas N. |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839215/ |
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