Induction of Human iPSC-Derived Cardiomyocyte Proliferation Revealed by Combinatorial Screening in High Density Microbioreactor Arrays

Inducing cardiomyocyte proliferation in post-mitotic adult heart tissue is attracting significant attention as a therapeutic strategy to regenerate the heart after injury. Model animal screens have identified several candidate signalling pathways, however, it remains unclear as to what extent these...

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Bibliographic Details
Main Authors: Titmarsh, Drew M., Glass, Nick R., Mills, Richard J., Hidalgo, Alejandro, Wolvetang, Ernst J., Porrello, Enzo R., Hudson, James E., Cooper-White, Justin J.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838928/