Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus

Higher order chromatin structure establishes domains that organize the genome and coordinate gene expression. However, the molecular mechanisms controlling transcription of individual loci within a topological domain (TAD) are not fully understood. The cystic fibrosis transmembrane conductance regul...

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Bibliographic Details
Main Authors: Yang, Rui, Kerschner, Jenny L., Gosalia, Nehal, Neems, Daniel, Gorsic, Lidija K., Safi, Alexias, Crawford, Gregory E., Kosak, Steven T., Leir, Shih-Hsing, Harris, Ann
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838340/